Monkeypox Cases In Us 2025 Update. The chief of the world health organization (who) declared that the rise in mpox cases constitutes a public health emergency of international concern (pheic), following. More than 500 mpox cases have been reported in the united states in 2025, according to cdc data, and relatively low levels of vaccination leave many at risk.

As of may 1, 2025, u.s. Monkeypox particles (red) found within an infected cell (blue) (picture: